catastrophe

(n) an event resulting in great loss and misfortune
- the whole city was affected by the irremediable calamity
- the earthquake was a disaster
calamity, tragedy, cataclysm, disaster,
(n) a state of extreme (usually irremediable) ruin and misfortune
- lack of funds has resulted in a catastrophe for our school system
- his policies were a disaster
disaster,
(n) a sudden violent change in the earth's surface cataclysm,

calamity tragedy cataclysm disaster